Paris St-Germain forward Neymar will have surgery on Saturday after fracturing a metatarsal and spraining an ankle during Sunday's Ligue 1 victory over Marseille.
Brazil team doctor Rodrigo Lasmar confirmed the news to reporters, and said the 26-year-old will be out for up to three months.
He expects Neymar to be fit in time for the World Cup in June.
But the £200 million world record signing will miss the rest of PSG's season, reports BBC.
PSG coach Unai Emery initially said Neymar had a "small chance" of facing Real Madrid in the Champions League next week, before Neymar's father said he would be out for "six to eight weeks".
Lasmar, in quotes reported by O Globo, said, "The operation will be in Belo Horizonte on Saturday morning, and the recovery takes from two and a half months to three months.
"Neymar is sad, but understands he has no alternative now. He will devote himself to being well as soon as possible".
PSG said, after "three days of planned care", it was a joint decision by the club's medical staff and the Brazilian national team to opt for surgery.
The striker joined PSG from Barcelona last August and has scored 29 goals in 30 games.
PSG are 14 points clear of second-placed Monaco in the league and on 6 March will host Champions League holders Real Madrid, trailing 3-1 from the first leg.
