The death toll from an outbreak of coronavirus in Italy has leapt by 627 to 4,032, officials said on Friday, an increase of 18.4 per cent - by far the largest daily rise in absolute terms since the contagion emerged a month ago.
On Thursday, Italy overtook China as the country to register most deaths from the highly contagious respiratory disease.
The total number of cases in Italy rose to 47,021 from a previous 41,035, a rise of 14.6 per cent, the Civil Protection Agency said.
In its most complete analysis of the outbreak yet published, the national health institute (ISS) said the average age of those who died was 78.5 years, with the youngest victim aged 31 and the oldest 103. The median age was 80.
Some 41 per cent of all those who died were aged between 80-89, with the 70-79 age group accounting for a further 35 per cent.
Italy has the oldest population in the world after Japan, with some 23 per cent of people aged over age 65. Medical experts say these demographics could explain why the death toll here is so much higher than anywhere else in the world.
The ISS report, based on a survey of 3,200 of the dead, said men accounted for 70.6 per cent of the deaths and women 29.4 per cent. The median age for the women who died was 82 against 79 for men.
By comparison, the median age of those who tested positive for the illness was 63.
A deeper analysis of 481 of the deceased showed that almost 99 per cent of them were suffering from one or more medical condition before catching the virus. Some 48.6 per cent had three or more previous pathologies.
A total 73.8 per cent had had high blood pressure, 34 per cent had diabetes and 30.1 per cent had heart disease.
On being admitted to hospital, 76 per cent had a fever, 73 per cent had breathing difficulties, 40 per cent had a cough and 8.0 per cent had diarrhea.
The median time between the onset of the first symptoms and subsequent death was eight days, with the median time spent in hospital just four days.
Of the 3,200 deaths reviewed in the survey, only nine were aged less than 40, all but one of them men.
